Publications

Recent selected

• Andreas J Gruber*, André V Olsen*, Barbara Hernando*, Kevin CL Cheng*, Clarissa Gerhäuser, Marina Torres, Francesco Favero, Daria Kiriy, Angel Fernández-Sanromán, Juan Maria Roldan-Romero, Lucy Barton, Diogo Pellegrina, G. Steven Bova, Daniel S Brewer, Mark N Brook, Benedikt Brors, Adam Butler, Géraldine Cancel-Tassin, Niall M Corcoran, Olivier Cussenot, Abraham Gihawi, Etsehiwot G Girma, Vincent J Gnanapragasam, Anis Hamid, Vanessa M Hayes, Housheng Hansen He, Christopher M Hovens, Eddie L Imada, G. Maria M Jakobsdottir, Chol-hee Jung, Francesca Khani, Zsofia Kote-Jarai, Philippe Lamy, Gregory Leeman, Massimo Loda, Pavlo Lutsik, Luigi Marchionni, Ramyar Molania, Anthony Papenfuss, Bernard Pope, Lucio R Queiroz, Tobias Rausch, Brian Robinson, Atef Sahli, Karina D Sørensen, Takafumi N. Yamaguchi , Sebastian Uhrig, Yaobo Xu, Claudio Zanettini, Pan Prostate Cancer Group (PPCG), Ronald Simon, Guido Sauter, Ros A Eeles, Colin S Cooper, Robert G Bristow, David C Wedge, Thorsten Schlomm, Geoff Macintyre#, Jüri Reimand#, Joachim Weischenfeldt#. Integrated signatures define mutational processes in prostate cancer (2026). Nature. Accepted in principle. Impact factor: 69.8

• Voßgröne, K.*, Favero, F.*, Kashyap, K., Rodríguez-González, F. G., Olsen, A. V., Li, X., Mardin, B. R., Weischenfeldt, J.#, and Sørensen, C. S.#. Enzyme family-centred approach identifies helicases as recurrent hemizygous tumour suppressor genes (2026). Science Advances. Impact factor: 12.5

• Hendriksen, J. D. L., A, Schlotmann, B. C. R. G., FG, Skjøth-Rasmussen, J., Yde, C. W., Nørøxe, D. S., Poulsen, H. S., Lassen, U., and Weischenfeldt, J.#. Resolving Clonal Evolution and Selection of Extrachromosomal DNA at Single-cell Resolution (2026). Genome Biol impact factor: 10.1

• Migle Mikutenaite*, Evdoxia Karadoulama*, Francesco Favero, Alessio Locallo, Francisco German Rodriguez Gonzalez, Daria Kiriy, Tina Keshavarzian, Kira Furlano, Markus Graefen, Robert G Bristow, Clarissa Gerhäuser, Christoph Plass, Guido Sauter, Ronald Simon, Mathieu Lupien, Sarah Minner, Thorsten Schlomm, Joachim Weischenfeldt#. Clonal Evolution and Transcriptional Plasticity Shape Metastatic Dissemination Routes in Prostate Cancer (2025). Nature Communications Impact factor: 17.7
  

• Christensen AH, Pan G, Marvig RL, Rodriguez Gonzalez FG, Vissing CR, Silajdzija E, Frosted R, Girma EG, Gabrielaite M, Jensen HK, Rossing K, Henriksen FL, Sandgaard NCF, Ahlberg G, Ghouse J, Lundegaard PR, Weischenfeldt J, Wadelius C, Bundgaard H., Gain-of-function enhancer variant near KCNB1 causes familial ST-depression syndrome. (2025) Eur Heart J.
  Impact factor: 39.3

• Aidan Flynn, Sebastian M Waszak, Joachim Weischenfeldt#. Somatic CpG hypermutation is associated with mismatch repair deficiency in cancer. (2024) Molecular Systems Biology
  Impact factor: 12.7
  

• Josephine D Hendriksen, Alessio Locallo, Simone Maarup, Olivia Debnath, Naveed Ishaque, Benedikte Hasselbach, Jane Skjøth-Rasmussen, Christina Westmose Yde, Hans S Poulsen, Ulrik Lassen, Joachim Weischenfeldt #. Immunotherapy drives mesenchymal tumor cell state shift and TME immune response in glioblastoma patients (2024) Neuro-oncology
  Impact factor: 15.9
  interview with Josephine and Joacim in the Neuro-oncology podcast
  “Now we know why successful treatment does not affect specific cancer cells” news coverage
  

• Dubois F, Sidiropoulos N, Weischenfeldt J #, Beroukhim R #. 2022. Structural variations in cancer and the 3D genome. Nat Rev Cancer
  Impact factor: 69.8
  

• Sidiropoulos N, Mardin BR, Rodríguez-González FG, Bochkov ID, Garg S, Stütz AM, Korbel JO, Aiden EL, Weischenfeldt J #. 2022. Somatic structural variant formation is guided by and influences genome architecture. Genome Res.
  Impact factor: 9.5

• Tulstrup, M., Soerensen, M., Hansen, J.W., Gillberg, L., Needhamsen, M., Kaastrup, K, Helin, K., Christensen, K., Weischenfeldt, J #., Grønbæk, K. #. TET2 mutations are associated with hypermethylation at key regulatory enhancers in normal and malignant hematopoiesis. Nature Commun, ​​12: 6061
  Impact factor: 17.7

• Li, Y., Roberts, N. D., Wala, J. A., Shapira, O., Schumacher, S. E., Kumar, K., Khurana, E., Waszak, S., Korbel, J. O., Haber, J. E., Imielinski, M., PCAWG, S. V. W. G., Weischenfeldt, J.#, Beroukhim, R #., Campbell, P. J. # (2020). Patterns of somatic structural variation in human cancer genomes. Nature, 578(7793), 112-121
  impact factor: 64.8, Web of Science “Highly cited paper” (top 1% of the academic field of Molecular Biology & Genetics).

• Rheinbay, E., Nielsen, M. M., Abascal, F., Wala, J. A., Shapira, O., Tiao, G., Hornshøj, H., Hess, J. M. …, Weischenfeldt, J. #, Beroukhim, R. #, Martincorena, I. #, Pedersen, J. S. #, Getz, G. # (2020). Analyses of non-coding somatic drivers in 2,658 cancer whole genomes. Nature, 578(7793), 102-111
  impact factor: 64.8, Web of Science “Highly cited paper” (top 1% of the academic field of Molecular Biology & Genetics)

• Gerhauser, C., Favero, F., Risch, T., Simon, R., Feuerbach, L., Assenov, Y., Heckmann, D., …, Sültmann, H., Brors, B., Sauter, G., Plass, C., Yaspo, M. L., Korbel, J. O., Schlomm, T., & Weischenfeldt, J. # (2018). Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories. Cancer Cell, 34(6), 996-1011.e8.
  Impact factor: 50.3

• Eskelund, C. W., Husby, S., Favero, F., Klausen, T. W., Rodriguez-Gonzalez, F. G., Kolstad, A., Pedersen, L. B., Räty, R. K., Geisler, C. H., Jerkeman, M., Weischenfeldt, J., & Grønbæk, K. (2020). Clonal hematopoiesis evolves from pre-treatment clones and stabilizes after end of chemotherapy in patients with MCL. Blood.
  Impact factor: 23.6

• Hansen, J. W., Pedersen, D. A., Larsen, L. A., Husby, S., Clemmensen, S. B., Hjelmborg, J., Favero, F., Weischenfeldt, J., Christensen, K., & Grønbæk, K. (2019). Clonal hematopoiesis in elderly twins: concordance, discordance and mortality. Blood.
  Impact factor: 23.6

• Weischenfeldt, J. *, Dubash, T., Drainas, A. …Glimm, H., & Korbel, J. O. (2017). Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking. Nat Genet, 49(1), 65-74.
  impact factor: 38.3

(For a full list of publications, go to Google Scholar)